BDBM50598872 CHEMBL5206165

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@@](C)(C1)C(=O)c1cccc(OC)c1)ccc3OC

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50598872   

TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataEC50:  193nMAssay Description:Agonist activity at rat MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataEC50:  951nMAssay Description:Agonist activity at rat DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]DPDPE from rat DOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]DAMGO from rat MOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50598872(CHEMBL5206165)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]U69593 from human KOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed