BDBM50598856 CHEMBL5174072::US20240207300, Compound 201

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2cc(Cl)c(C)nc12

InChI Key InChIKey=IEYFYHAQSNSXRD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598856   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics

Curated by ChEMBL

LigandBDBM50598856(CHEMBL5174072 | US20240207300, Compound 201)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetMyelin transcription factor 1(Human)
Repare Therapeutics

US Patent

LigandBDBM50598856(CHEMBL5174072 | US20240207300, Compound 201)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Detection of Myt1 kinase activity utilized a recombinant human Myt1 kinase assay measuring the hydrolysis of ATP using a commercially available ADP-G...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/4/2024
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL