BDBM50598534 CHEMBL5206298

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)c2ccncn2)cc1Nc1nccc(n1)-c1cn(CCCO)c2ccccc12

InChI Key InChIKey=GGHJFMZZBAABTI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50598534   

TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598534(CHEMBL5206298)
Affinity DataIC50: 590nMAssay Description:Inhibition of wild type EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598534(CHEMBL5206298)
Affinity DataIC50: 41nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598534(CHEMBL5206298)
Affinity DataIC50: 161nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598534(CHEMBL5206298)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed