BDBM50598528 CHEMBL5201846

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)c2ccncn2)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

InChI Key InChIKey=YISSGLCFSAVMBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50598528   

TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598528(CHEMBL5201846)
Affinity DataIC50: 29nMAssay Description:Inhibition of wild type EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598528(CHEMBL5201846)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598528(CHEMBL5201846)
Affinity DataIC50: 242nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
College of Pharmacy of Liaoning University

Curated by ChEMBL
LigandPNGBDBM50598528(CHEMBL5201846)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed