BDBM50598319 CHEMBL5194724

SMILES NS(=O)(=O)c1cccc(NC(=S)NC(=O)c2ccc3OCOc3c2)c1

InChI Key InChIKey=KDHCYLDWEYOHEV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598319   

TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598319(CHEMBL5194724)
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598319(CHEMBL5194724)
Affinity DataIC50: 110nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598319(CHEMBL5194724)
Affinity DataIC50: 173nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as reduction in BzATP-induced activity incubated for 5 to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed