BDBM50598318 CHEMBL5205239

SMILES Clc1ncccc1NC(=S)NC(=O)c1ccc2OCOc2c1

InChI Key InChIKey=DYJDDJVVVMHYEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50598318   

TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598318(CHEMBL5205239)
Affinity DataIC50: 3.59E+4nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598318(CHEMBL5205239)
Affinity DataIC50: 935nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598318(CHEMBL5205239)
Affinity DataIC50: 34nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598318(CHEMBL5205239)
Affinity DataIC50: 34nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as reduction in BzATP-induced activity incubated for 5 to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598318(CHEMBL5205239)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed