BDBM50598316 CHEMBL5184613

SMILES Oc1c(Cl)cc(NC(=S)NC(=O)c2ccc3OCOc3c2)cc1Cl

InChI Key InChIKey=CJAJOVQFKNMCSF-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50598316   

TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataIC50: 247nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataIC50: 7.64E+3nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataIC50: 1.64E+3nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataEC50:  8.27E+3nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.1 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataEC50:  1.09E+4nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.2 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598316(CHEMBL5184613)
Affinity DataEC50:  1.08E+4nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.4 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed