BDBM50598315 CHEMBL5186938

SMILES Oc1ccc(NC(=S)NC(=O)c2ccc3OCOc3c2)cc1

InChI Key InChIKey=IPAXQJYDJZNAFF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50598315   

TargetP2X purinoceptor 2(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598315(CHEMBL5186938)
Affinity DataIC50: 6.43E+3nMAssay Description:Antagonist activity against human P2X2R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598315(CHEMBL5186938)
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 5(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598315(CHEMBL5186938)
Affinity DataIC50: 2.76E+4nMAssay Description:Antagonist activity against human P2X5R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598315(CHEMBL5186938)
Affinity DataIC50: 902nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598315(CHEMBL5186938)
Affinity DataIC50: 1.11E+3nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as reduction in BzATP-induced activity incubated for 5 to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed