BDBM50598193 CHEMBL5178704

SMILES Cc1ccc(C\N=C2/NC(=O)\C(S2)=C2/CCNC(=O)c3[nH]ccc23)cc1

InChI Key InChIKey=QAEQJFJYLBGTKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50598193   

TargetDNA topoisomerase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50598193(CHEMBL5178704)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 assessed as reduction in pBR322 DNA relaxation incubated for 1 hrs measured by agarose gel electrophoresis me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed