BDBM50597876 CHEMBL5187594

SMILES CCC(CC)n1ncc2c(cc(cc12)C#N)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=QTOSIAXSQPPVAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597876   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597876(CHEMBL5187594)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597876(CHEMBL5187594)
Affinity DataIC50: 13nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed