BDBM50597818 CHEMBL5197817

SMILES CC1COc2cc(ccc2-c2nc(sc12)-c1ncnn1-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=UUEQJJPDWJRBAN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597818   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Pharmaron Beijing

Curated by ChEMBL

LigandBDBM50597818(CHEMBL5197817)Copy SMILESCopy InChI

Affinity DataIC50: 130nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/22/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Pharmaron Beijing

Curated by ChEMBL

LigandBDBM50597818(CHEMBL5197817)Copy SMILESCopy InChI

Affinity DataIC50: 330nMAssay Description:Inhibition of PI3Kalpha (unknown origin) preincubated with compound for 20 mins followed by substrate addition measured after 120 mins in presence of...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/22/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL