BDBM50597517 CHEMBL5171118

SMILES C[N+]1(C)CCC(CC1)Oc1ccc(C=Cc2ccccc2)cc1

InChI Key InChIKey=JRAZMHFHZFKHQJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597517   

TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597517(CHEMBL5171118)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597517(CHEMBL5171118)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597517(CHEMBL5171118)
Affinity DataKi:  368nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChR expressed in SH-EP1 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597517(CHEMBL5171118)
Affinity DataKi:  613nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed