BDBM50597347 CHEMBL5206121

SMILES Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)CNC(=O)c1ccncc1

InChI Key InChIKey=LEBSTCDZKUSVOY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597347   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597347(CHEMBL5206121)
Affinity DataIC50: 34nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597347(CHEMBL5206121)
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using CRRKSLVGTPYWMAPE peptide as substrate assessed as inhibition of autophosphorylation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50597347(CHEMBL5206121)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50597347(CHEMBL5206121)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed