BDBM50597265 CHEMBL5197108

SMILES O[C@@H]1CC[C@@H](C1)NC(=O)c1cc2cccc(-c3cc(ccc3Cl)C#N)c2o1

InChI Key InChIKey=ULGBDVGBFRPXRT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50597265   

TargetCeramide glucosyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50597265(CHEMBL5197108)
Affinity DataEC50:  0.0470nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed