BDBM50597152 CHEMBL5191932

SMILES Cc1[nH]nc(c1-c1ccc(cc1)-c1ccc(c(C)c1C)S(N)(=O)=O)-c1cc(C)nc(C)c1

InChI Key InChIKey=HAXJROUNDJLRHV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597152   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597152(CHEMBL5191932)
Affinity DataIC50: 325nMAssay Description:Inhibition of full-length wild type LRRK2 (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADAPTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597152(CHEMBL5191932)
Affinity DataIC50: 76nMAssay Description:Inhibition of full-length LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mouse)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597152(CHEMBL5191932)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of mouse full-length LRRK2 G2019S mutant transfected in HEK293 cells using LRRKtide as substrate in presence of ATP by incubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed