BDBM50597144 CHEMBL5205363

SMILES NS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1c[nH]nc1-c1ccncc1

InChI Key InChIKey=WEYZMTHVWCJUGC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597144   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597144(CHEMBL5205363)
Affinity DataIC50: 247nMAssay Description:Inhibition of full-length wild type LRRK2 (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADAPTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597144(CHEMBL5205363)
Affinity DataIC50: 24nMAssay Description:Inhibition of full-length LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mouse)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597144(CHEMBL5205363)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibition of mouse full-length LRRK2 G2019S mutant transfected in HEK293 cells using LRRKtide as substrate in presence of ATP by incubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed