BDBM50597020 CHEMBL5193659

SMILES Fc1ccc(cc1Cl)C(NC(=O)[C@@H]1CNC(=O)C1)c1ccc(F)c(n1)C(F)(F)F

InChI Key InChIKey=VVNDRVPPZFQJLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50597020   

TargetSodium channel protein type 8 subunit alpha(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50597020(CHEMBL5193659)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Nav1.8 channel stably expressed in HEK293 cells assessed as sodium current flow at holding potential of -90mV by whole-cell volta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed