BDBM50596162 CHEMBL5185644

SMILES Fc1ccc(cn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1

InChI Key InChIKey=ZSBQCAFIVMPZNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596162   

TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596162(CHEMBL5185644)
Affinity DataIC50: 800nMAssay Description:Inhibition of ELOVL1 (unknown origin) using C22-acyl-CoA as substrate by radiometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596162(CHEMBL5185644)
Affinity DataIC50: 23nMAssay Description:Inhibition of ELOVL1 in human HEK2936E cells assessed as reduction of C26:0 LPC synthesis incubated for 48 hrs by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed