BDBM50596145 CHEMBL5199478

SMILES C[C@H](C(=O)Nc1ccn(n1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=ULZFXKNWGSBUBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596145   

TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596145(CHEMBL5199478)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ELOVL1 (unknown origin) using C22-acyl-CoA as substrate by radiometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596145(CHEMBL5199478)
Affinity DataIC50: 38nMAssay Description:Inhibition of ELOVL1 in human HEK2936E cells assessed as reduction of C26:0 LPC synthesis incubated for 48 hrs by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed