BDBM50595997 CHEMBL5183006

SMILES CC(=O)N1CCN(Cc2ccc(cc2)-c2[nH]c3cc(F)cc4C(=O)NCCc2c34)CC1

InChI Key InChIKey=AEUHXAJXFXCXEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595997   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595997(CHEMBL5183006)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP1 using NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595997(CHEMBL5183006)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed