BDBM50595874 CHEMBL5197755

SMILES [H][C@@]12NC(=N)N[C@]11N(C[C@H](NC(=O)c3cccc4c3OCCC4(C)C)C1(O)O)C(=N)N[C@H]2CN1C(=O)CNC1=O

InChI Key InChIKey=ZYIDVGBHOFGXRR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595874   

TargetSodium channel protein type 9 subunit alpha(Human)
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50595874(CHEMBL5197755)
Affinity DataIC50: 85nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50595874(CHEMBL5197755)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50595874(CHEMBL5197755)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed