BDBM50595828 CHEMBL5203217

SMILES [H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)c1ccc(NC(=O)c2cccc(Nc3cc(NC(=O)C4CC4)nnc3C(=O)NC([2H])([2H])[2H])c2OC)cc1

InChI Key InChIKey=UTRBMJDIGONTMK-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595828   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50595828(CHEMBL5203217)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed