BDBM50595781 CHEMBL5195510::US11746103, EX-05

SMILES Cc1cccc2c(Nc3ccnc(Nc4ccc(CC5CCNCC5)cc4)n3)cnnc12

InChI Key InChIKey=UFQRQSWJIOMAPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595781   

TargetTGF-beta receptor type-1(Human)
Sumitomo Pharma Oncology

US Patent
LigandPNGBDBM50595781(CHEMBL5195510 | US11746103, EX-05)
Affinity DataIC50: 100nMAssay Description:Binding of an Alexa Fluor™ conjugate or “tracer” to a kinase is detected by addition of an Eu-labeled anti-tag antibody. Binding of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Sumitomo Pharma Oncology

US Patent
LigandPNGBDBM50595781(CHEMBL5195510 | US11746103, EX-05)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Alexa Fluor labeled tracer 178 from ALK5 (unknown origin) using anti-GST antibody incubated for 60 mins by TR-FRET based LanthaScreen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed