BDBM50595541 CHEMBL5190291

SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1nc2cc(cc(F)c2[nH]1)N1CCOCC1)C(F)(F)F

InChI Key InChIKey=RONUOMGBOIHWKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595541   

TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50595541(CHEMBL5190291)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human recombinant CXCR3 expressed in CHO-K1 cells measured after 10 mins in presence of CXCL10 by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50595541(CHEMBL5190291)
Affinity DataIC50: 306nMAssay Description:Antagonist activity at human recombinant CXCR3 in human venous blood assessed as receptor internalization measured for 30 mins in presence of CXCL10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed