BDBM50595449 CHEMBL5197253

SMILES O=C(Cn1cnc2cccnc12)N1CCN(CC1)c1cccnc1-c1nc2ccccc2[nH]1

InChI Key InChIKey=SNKCPHWBRAKKNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595449   

TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50595449(CHEMBL5197253)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at recombinant human CXCR3 expressed in human CHO-K1 cells co-expressing Galpha15 incubated for 10 mins by Fluo-4AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50595449(CHEMBL5197253)
Affinity DataIC50: 785nMAssay Description:Inhibition of CXCR3 receptor internalization in human venous whole blood incubated for 30 mins by flow cytometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed