BDBM50595397 CHEMBL4467651

SMILES CC1=C\C(=N\OC(=O)c2ccccc2C)C(C)=CC1=O

InChI Key InChIKey=KWDBXGNIGYVOBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595397   

TargetSerine/threonine-protein kinase PLK1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595397(CHEMBL4467651)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of 5-carboxyfluoresceinGPMQSpTPLNG-OH peptide binding to N-terminal His7-tagged human PLK1 (326 to 603 residues) PBD expressed in Escheric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595397(CHEMBL4467651)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GPMQTSpTPKNG-OH peptide binding to PLK2 (355 to 685 residues) PBD (unknown origin) preincubated for 1 hrs with com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595397(CHEMBL4467651)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed