BDBM50595393 CHEMBL5170038

SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1cncn1CCCCc1cn(Cc2ccc(Oc3ccccc3)cc2F)nn1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(O)(O)=O)C(N)=O

InChI Key InChIKey=RZLGHTUEKVZIMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595393   

TargetSerine/threonine-protein kinase PLK1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595393(CHEMBL5170038)
Affinity DataIC50: 25nMAssay Description:Inhibition of Myc-tagged PLK1 PBD (unknown origin) expressed in HEK293T cells using 5CF-GPMQSpTPLNG-NH2 as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595393(CHEMBL5170038)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Myc-tagged PLK2 PBD (unknown origin) expressed in HEK293T cells using 5CF-GPMQTSpTPKNG-NH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595393(CHEMBL5170038)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of Myc-tagged PLK3 PBD (unknown origin) expressed in HEK293T cells using 5CF-PLATSpTPKNG-NH2 as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed