BDBM50595000 CHEMBL5182136

SMILES COc1cc(OC)cc(\C=C\c2cc(=O)oc3c4cc(oc4ccc23)-c2cc(OC)cc(OC)c2)c1

InChI Key InChIKey=DXJLEIVEYFLNDY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50595000   

TargetAcetylcholinesterase(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50595000(CHEMBL5182136)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of AChE (unknown origin) incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50595000(CHEMBL5182136)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of BChE (unknown origin) incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50595000(CHEMBL5182136)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in baculovirus using Rh-EVNLDAEFK-Quencher as substrate incubated for 60 mins by measuring increase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50595000(CHEMBL5182136)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of cox-2 (unknown origin) incubated for 5 mins by 96-well plate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50595000(CHEMBL5182136)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human LOX-5 in presence of LOX substrate solution incubated for 10 mins by Varioskan-flash microplate spectrophotometer readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed