BDBM50594973 CHEMBL5169811

SMILES Nc1nc(nc2n(C[C@H]3CN(Cc4nccs4)CCO3)nnc12)C(F)(F)F

InChI Key InChIKey=VNLPYEMGHGDRRZ-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50594973   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE8A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/21/2023
Entry Details
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TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/21/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE8A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE8A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
4/19/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Human)
Shaoxing University

Curated by ChEMBL

LigandBDBM50594973(CHEMBL5169811)Copy SMILESCopy InChI

Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
4/19/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL