BDBM50594961 CHEMBL5201233

SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=S)SCC(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccccc1F

InChI Key InChIKey=JLVKZAFEAVEIAS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50594961   

TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 140nMAssay Description:Inhibition of full-length KDM1A (unknown origin) expressed in Escherichia coli BL21 DE by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAO-A (unknown origin) by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAO-B (unknown origin) by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 140nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 140nMAssay Description:Inhibition of LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant MAO-A (unknown origin) by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594961(CHEMBL5201233)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant MAO-B (unknown origin) by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed