BDBM50594748 CHEMBL5202670

SMILES CN1CN(Cc2cnc(Nc3cc(C)nn3C)nc12)c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=MCEWMWAJAOMTBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594748   

TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594748(CHEMBL5202670)
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length wild-type BTK (unknown origin) measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594748(CHEMBL5202670)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK C481S mutant (unknown origin) measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed