BDBM50594746 CHEMBL5193128

SMILES NC(=O)C1C2NCC[C@@H](C3CCN(CC3)C(=O)C=C)N2N=C1c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PZWSKESWDIFAFK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594746   

TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 44nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 50nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 88nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed