BDBM50594745 CHEMBL5187554

SMILES CC#CC(=O)N1CCC[C@H]1n1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)ncnc12

InChI Key InChIKey=CVBABGVEYUMHNU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594745   

TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 126nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 368nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 46nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 16nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed