BDBM50594719 CHEMBL5186583

SMILES CCc1nnc2c(Nc3ccc(cc3)C(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)nc3ccccc3n12

InChI Key InChIKey=IFPNFAIDTHYHMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594719   

TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594719(CHEMBL5186583)
Affinity DataIC50: 39nMAssay Description:Inhibition of GST-tagged EGFR (unknown origin) assessed as phosphorylation level using biotinylated peptide as substrate in presence of ATP by HTScan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594719(CHEMBL5186583)
Affinity DataIC50: 93nMAssay Description:Inhibition of GST-fused EGFR (unknown origin) in presence of ATP by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTubulin beta-4B chain(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50594719(CHEMBL5186583)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of beta-tubulin polymerization in human HCT-116 cells using TMB substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed