BDBM50594718 CHEMBL5182231

SMILES O=C(Cc1ccccc1)Nc1cccc(c1)-c1nc2SCCn2c1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=VPSPBDWFZHKYBM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594718   

TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594718(CHEMBL5182231)
Affinity DataIC50: 36nMAssay Description:Inhibition of human EGFR expressed in baculovirus expression system using CAGAGAIETDKEYYTVKD as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594718(CHEMBL5182231)
Affinity DataIC50: 66nMAssay Description:Inhibition of human EGFR T790M mutant expressed in baculovirus expression system using CAGAGAIETDKEYYTVKD as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594718(CHEMBL5182231)
Affinity DataIC50: 52nMAssay Description:Inhibition of human IGF1R expressed in baculovirus expression system using poly GT peptide as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed