BDBM50594703 CHEMBL5208951

SMILES COc1cc2c(Nc3ccc(cc3)C(=O)\C=C\c3nc(C)c(C)nc3C)ncnc2c(OC)c1OC

InChI Key InChIKey=UZXQWOTYFRAWSY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50594703   

TargetAcetylcholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 100nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 4.74E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of amyloid beta 1 to 42 (unknown origin) at 10 uM relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by fluorimetric based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594703(CHEMBL5208951)
Affinity DataIC50: 2.24E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed