BDBM50594497 CHEMBL4441501

SMILES c1nc(c2c(n1)n(cn2)[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

InChI Key InChIKey=ZKHQWZAMYRWXGA-UHFFFAOYSA-N

Data  7 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50594497   

TargetP2X purinoceptor 1(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 2(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.05E+4nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594497(CHEMBL4441501)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed