BDBM50594350 CHEMBL5179238

SMILES C[C@H]1CC[C@H](N1c1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccnc1

InChI Key InChIKey=WALAECWNQSIPAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594350   

LigandPNGBDBM50594350(CHEMBL5179238)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594350(CHEMBL5179238)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kdelta expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594350(CHEMBL5179238)
Affinity DataIC50: 7.94E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kalpha expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594350(CHEMBL5179238)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kbeta expressed in baculovirus infected Sf21 insect cells incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed