BDBM50594348 CHEMBL5182539

SMILES [H][C@]12C[C@H](N(c3nc(N)nc(N)c3C#N)[C@@]1([H])CCCC2)c1nc2cccc(Cl)c2c(=O)n1N1CCOCC1

InChI Key InChIKey=KHPDHBLSVBTZFA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594348   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
West China Hospital

Curated by ChEMBL

LigandBDBM50594348(CHEMBL5182539)Copy SMILESCopy InChI

Affinity DataIC50: 3.12E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/21/2023
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
West China Hospital

Curated by ChEMBL

LigandBDBM50594348(CHEMBL5182539)Copy SMILESCopy InChI

Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kdelta expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/21/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL