BDBM50594268 CHEMBL5178746

SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc12)c1ccccc1

InChI Key InChIKey=JSDGGEOTFRHCLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594268   

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human PARP3 expressed in baculovirus expression system using anchored-histone proteins as substrate incubated for 1 hr by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human PARP3 using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed