BDBM50594143 CHEMBL5190398

SMILES CCN([C@H]1CC[C@@H](CC1)N(C)C)c1cc(cc2c(NCc3c(C)cc(C)[nH]c3=O)nccc12)-c1cnc(nc1)N1CCN(C)CC1

InChI Key InChIKey=LDQFRHVZVMAXPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50594143   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594143(CHEMBL5190398)
Affinity DataIC50: 5nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed