BDBM50594142 CHEMBL5195001

SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1cc2c(ccn2c(C(=C)N2CCOCC2)c1C)-c1ccnc(c1)N(C)C

InChI Key InChIKey=GZNIVRZVCVETGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50594142   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594142(CHEMBL5195001)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed