BDBM50594137 CHEMBL5205079

SMILES CC(C)Oc1cc(C)[nH]c(=O)c1CNC(=O)c1ccc2c(cc(C)nc2c1C)-c1ccc(nc1)N1CCN(C)CC1

InChI Key InChIKey=KCKVJJBMDCADSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594137   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594137(CHEMBL5205079)
Affinity DataIC50: 13nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594137(CHEMBL5205079)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed