BDBM50594124 CHEMBL5186430

SMILES CC(C)n1ncc2cc(cc(-c3ccc(nc3)N3CCN(CCOCCC(=O)Nc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)CC3)c12)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=MZCKTSGGYXUQDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594124   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594124(CHEMBL5186430)
Affinity DataIC50: 7nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594124(CHEMBL5186430)
Affinity DataIC50: 7nMAssay Description:Inhibition of EZH2 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed