BDBM50594108 CHEMBL5175660

SMILES COc1cc2nc(NCCCCCN(C)C)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC

InChI Key InChIKey=VUDCYLLEDSGQEA-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594108   

TargetREST corepressor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594108(CHEMBL5175660)
Affinity DataKd:  127nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594108(CHEMBL5175660)
Affinity DataKi:  2.79E+3nMAssay Description:Inhibition of G9a (unknown origin) assessed as reduction in substrate methylation using histone H3 and SAM as substrate measured after 15 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed