BDBM50594081 CHEMBL5199513

SMILES COc1cc2nc(NCCCN(C)C)nc(NC3CCN(C)CC3)c2cc1OC

InChI Key InChIKey=SZEBWNUWNIQDCX-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594081   

TargetREST corepressor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594081(CHEMBL5199513)
Affinity DataKd:  1.49E+3nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594081(CHEMBL5199513)
Affinity DataKi:  4.17E+3nMAssay Description:Inhibition of G9a (unknown origin) assessed as reduction in substrate methylation using histone H3 and SAM as substrate measured after 15 to 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed