BDBM50593999 CHEMBL5198984

SMILES NC(=O)c1ccc(OCC2CCCCC2)cc1F

InChI Key InChIKey=LSOUNQHPJFJTGF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50593999   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 960nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 955nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP14 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593999(CHEMBL5198984)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged TNKS2 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed