BDBM50593923 CHEMBL5195030

SMILES CC[C@@H](Nc1nc(NCc2cnc(C)cc2C)c2ncn(C(C)C)c2n1)[C@H](C)O

InChI Key InChIKey=DLPIYBKBHMZCJI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50593923   

TargetCyclin-dependent kinase 2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593923(CHEMBL5195030)
Affinity DataIC50: 5nMAssay Description:Inhibition of human full-length recombinant CDK2 (1 to 298 residues) expressed in baculovirus infected Sf21 insect cells in presence of ATP by enzyma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593923(CHEMBL5195030)
Affinity DataIC50: 26nMAssay Description:Inhibition of human full-length recombinant CDK4 (1 to 303 residues) expressed in baculovirus infected Sf21 insect cells in presence of ATP by enzyma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593923(CHEMBL5195030)
Affinity DataKi:  5nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593923(CHEMBL5195030)
Affinity DataKi:  578nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed