BDBM50593816 CHEMBL5191459

SMILES CN1C(=O)CN(C2CCOCC2)c2nc(Nc3cn4ncnc4cc3C)ncc12

InChI Key InChIKey=MZQKKBHRPQCGSA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50593816   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human native full length DNA-PK by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 187nMAssay Description:Inhibition of human PI3Kalpha by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 830nMAssay Description:Inhibition of human PI3Kbeta by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 281nMAssay Description:Inhibition of human PI3Kgamma by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 758nMAssay Description:Inhibition of human PI3Kdelta by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50593816(CHEMBL5191459)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed