BDBM50593635 CHEMBL5205867

SMILES C[C@H]1C[C@@H](Nc2ccc(cc2)C#N)c2cc(ccc2N1C(C)=O)-c1cc[nH]n1

InChI Key InChIKey=DFHREBKXJWXHKG-UHFFFAOYSA-N

Data  7 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50593635   

TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  2nMAssay Description:Binding affinity to BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  301nMAssay Description:Inhibition of poly His-tagged BRD4 BD1 (unknown origin) (71 to 94 residues) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  2nMAssay Description:Inhibition of poly His-tagged BRD4 BD2 (unknown origin) (348 to 455 residues) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  490nMAssay Description:Binding affinity to BDR2-BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  6nMAssay Description:Binding affinity to BDR2- BD2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  301nMAssay Description:Binding affinity to BDR4-BD1 (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50593635(CHEMBL5205867)
Affinity DataKd:  2nMAssay Description:Binding affinity to BDR4- BD2 (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed